Multiple Sclerosis (MS) Drugs

| Avonex | Betaseron | Betaferon | Copaxone | Rebif |

 

Avonex (interferon beta-1a)

What is Avonex ?

Avonex is a drug used in the treatment of multiple sclerosis. It is from a class of drugs known as interferons.

Interferon beta-1a is a recombinant DNA produced synthetic of naturally occurring proteins.

Interferons are cytokines. Three major classes of interferon have been identified - interferon alpha, interferon beta and interferon gamma. Interferon alpha and beta form the Type I class of interferons and Interferon gamma is a Type II interferon.

Indicated and approved for use in Multiple Sclerosis (MS) are Interferon beta-1a and Interferon beta-1b.

Interferons are species specific. In other words, the effects and results of interferon therapy and animal experimentation is difficult to apply across the human-animal species barriers since the effects they have within any given species are different.

The specific interferon-induced proteins and mechanisms by which interferon beta-1a exerts its effects in multiple sclerosis (MS) have not been fully defined.

Avonex is administered by intramuscular injection (injection directly into the muscle) once weekly.

 

 

 

Multiple Sclerosis

Depression, suicidal ideation, and suicide attempts have been reported to occur with increased frequency in patients receiving interferon compounds to treat multiple sclerosis, inc. Avonex, Betaseron and Rebif.

Cause of Multiple Sclerosis

The cause of multiple sclerosis remains a mystery. Many different causes have been proposed and investigated but as yet the cause of multiple sclerosis remains elusive... Read More