Multiple Sclerosis (MS) Drugs

| Avonex | Betaseron | Betaferon | Copaxone | Rebif |

 

Rebif (interferon beta-1a)

What is Rebif ?

Rebif is a drug used in the treatment of multiple sclerosis. It is from a class of drugs known as interferons.

Interferon beta-1a is a recombinant DNA produced synthetic of naturally occurring proteins.

Interferons are cytokines. Three major classes of interferon have been identified - interferon alpha, interferon beta and interferon gamma. Interferon alpha and beta form the Type I class of interferons and Interferon gamma is a Type II interferon.

Interferons are species specific. The effects and results of interferon therapy and animal experimentation is difficult to apply across the human-animal species barriers since the effects they have within any given species are different.

The specific interferon-induced proteins and mechanisms by which interferon beta-1a exerts its effects in multiple sclerosis (MS) have not been fully defined.

Rebif is administered by subcutaneous injection (injection under the skin) three times weekly.

 

 

 

 

 

Multiple Sclerosis

Depression, suicidal ideation, and suicide attempts have been reported to occur with increased frequency in patients receiving interferon compounds to treat multiple sclerosis, inc. Avonex, Betaseron and Rebif.

Symptoms of Multiple Sclerosis

The symptoms of multiple sclerosis are varied and can occur suddenly, then disappear again just as quickly. There are no specific sets of symptoms applicable to any of the types of multiple sclerosis. Additionally, symptoms of multiple sclerosis tend to vary considerably from one person to another and also to be distant in time... Read More